Hungarian 
This issue represents a significant global health threat driven by population growth, increasing food consumption — especially meat — and the excessive use of antibiotics. The widespread use of antibiotics in human and veterinary medicine (AB), and colistin (a polymyxin antibiotic) in veterinary medicine facilitates the emergence of colistin-resistant genes, such as mcr-1contexts.
Some notable bacteria of great concern include carbapenem-resistant Acinetobacter baumannii, third-generation cephalosporin-resistant Escherichia coli, and oxacillin-resistant Staphylococcus aureus. The presence and prevalence of these bacteria are strongly associated with AMU.
Global patterns suggest that veterinary antimicrobial usage will rise in the future, particularly in low- and middle-income countries. Consequently, the prevalence of colistin resistance among bacteria is expected to increase. Various European and global reports on colistin resistance and AMR emphasize the urgent need for a One Health approach — a holistic, multidisciplinary strategy — to address this issue.
Encouragingly, there has been a substantial decrease in AMU, including colistin usage, in some countries, though variations among nations remain.
The ongoing challenges of AMR underscore the critical need for coordinatedglobal efforts to prevent its further spread. Addressing this issue will require robust international collaboration and sustained commitment to reducing AMU across sectors.